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TaKaRa open reading frame encoding icre
Cx3cr1-CreERT2 rat creation and characterization overview. ( A ) The Cx3cr1-CreERT2 DNA was injected into Long Evans (LE) rat embryos. ( B ) The double-floxed inverted <t>open</t> <t>reading</t> <t>frame</t> (DIO) was used to produce the DIO-mCherry rat for Cre-dependent expression of the mCherry fluorescent protein in any cells that express Cre. ( C ) The DIO-mCherry rat was crossed with the Cx3cr1-CreERT2 and treated with tamoxifen (TAM) to fluorescently label Cx3cr1 expressing cells such as microglia in the brain. Created in BioRender. Harvey, B. (2025) https://BioRender.com/lf2aj0o .
Open Reading Frame Encoding Icre, supplied by TaKaRa, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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open reading frame encoding icre - by Bioz Stars, 2026-04
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Obio Technology Corp Ltd cdnas encoding the full open reading frames of human alkbh5
Cx3cr1-CreERT2 rat creation and characterization overview. ( A ) The Cx3cr1-CreERT2 DNA was injected into Long Evans (LE) rat embryos. ( B ) The double-floxed inverted <t>open</t> <t>reading</t> <t>frame</t> (DIO) was used to produce the DIO-mCherry rat for Cre-dependent expression of the mCherry fluorescent protein in any cells that express Cre. ( C ) The DIO-mCherry rat was crossed with the Cx3cr1-CreERT2 and treated with tamoxifen (TAM) to fluorescently label Cx3cr1 expressing cells such as microglia in the brain. Created in BioRender. Harvey, B. (2025) https://BioRender.com/lf2aj0o .
Cdnas Encoding The Full Open Reading Frames Of Human Alkbh5, supplied by Obio Technology Corp Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Twist Bioscience plasmid constructs encoding amino acids 2–282 of prv pul36 with in-frame n-terminal strep-tags
Cx3cr1-CreERT2 rat creation and characterization overview. ( A ) The Cx3cr1-CreERT2 DNA was injected into Long Evans (LE) rat embryos. ( B ) The double-floxed inverted <t>open</t> <t>reading</t> <t>frame</t> (DIO) was used to produce the DIO-mCherry rat for Cre-dependent expression of the mCherry fluorescent protein in any cells that express Cre. ( C ) The DIO-mCherry rat was crossed with the Cx3cr1-CreERT2 and treated with tamoxifen (TAM) to fluorescently label Cx3cr1 expressing cells such as microglia in the brain. Created in BioRender. Harvey, B. (2025) https://BioRender.com/lf2aj0o .
Plasmid Constructs Encoding Amino Acids 2–282 Of Prv Pul36 With In Frame N Terminal Strep Tags, supplied by Twist Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/plasmid constructs encoding amino acids 2–282 of prv pul36 with in-frame n-terminal strep-tags/product/Twist Bioscience
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Taconic Biosciences human cdna encoding the open reading frame for g6pc1 - c.247c > t ( g6pc1 -r83c)
The 10–12-week-old heterozygous (mR83/huR83C) mice, not fasted, were treated by systemic administration of BEAM-301 and the target site sequence was analyzed one week later via next-generation sequencing (NGS). a Target site sequence for p.R83C to p.R83 correction, the p.R83 synonymous variant and the pathogenic p.Y85H bystander variant. Nucleotides on the complementary strand edited by BEAM-301 are bracketed. b Correlation of dose levels of BEAM-301 to the editing efficiency for the conversion of the p.R83C ( <t>G6PC1</t> - c.247C > T ) variant to wild-type p.R83 ( G6PC1 - c.247 C ) along with the p.Y85H mutation. The n numbers for each dosage of BEAM-301 in mg/kg are listed. c Allele frequencies resulting from dosing heterozygous mice at 1.5 mg/kg (301H): p.R83C to p.R83 (correction); p.Y85H bystander mutation; Uncorrected (synonymous) editing (R83C); and Indels ( n = 5). Statistics were performed using a two-tailed unpaired T test. Data are presented as Mean values ± SEM, and individual data points for each animal are displayed. * denotes p < 0.05, ** denotes p value < 0.005.
Human Cdna Encoding The Open Reading Frame For G6pc1 C.247c > T ( G6pc1 R83c), supplied by Taconic Biosciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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LGC Genomics GmbH antibody encoding open reading frames
The 10–12-week-old heterozygous (mR83/huR83C) mice, not fasted, were treated by systemic administration of BEAM-301 and the target site sequence was analyzed one week later via next-generation sequencing (NGS). a Target site sequence for p.R83C to p.R83 correction, the p.R83 synonymous variant and the pathogenic p.Y85H bystander variant. Nucleotides on the complementary strand edited by BEAM-301 are bracketed. b Correlation of dose levels of BEAM-301 to the editing efficiency for the conversion of the p.R83C ( <t>G6PC1</t> - c.247C > T ) variant to wild-type p.R83 ( G6PC1 - c.247 C ) along with the p.Y85H mutation. The n numbers for each dosage of BEAM-301 in mg/kg are listed. c Allele frequencies resulting from dosing heterozygous mice at 1.5 mg/kg (301H): p.R83C to p.R83 (correction); p.Y85H bystander mutation; Uncorrected (synonymous) editing (R83C); and Indels ( n = 5). Statistics were performed using a two-tailed unpaired T test. Data are presented as Mean values ± SEM, and individual data points for each animal are displayed. * denotes p < 0.05, ** denotes p value < 0.005.
Antibody Encoding Open Reading Frames, supplied by LGC Genomics GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Twist Bioscience e. coli ftsw open reading frame encoding the e289g residue change
The 10–12-week-old heterozygous (mR83/huR83C) mice, not fasted, were treated by systemic administration of BEAM-301 and the target site sequence was analyzed one week later via next-generation sequencing (NGS). a Target site sequence for p.R83C to p.R83 correction, the p.R83 synonymous variant and the pathogenic p.Y85H bystander variant. Nucleotides on the complementary strand edited by BEAM-301 are bracketed. b Correlation of dose levels of BEAM-301 to the editing efficiency for the conversion of the p.R83C ( <t>G6PC1</t> - c.247C > T ) variant to wild-type p.R83 ( G6PC1 - c.247 C ) along with the p.Y85H mutation. The n numbers for each dosage of BEAM-301 in mg/kg are listed. c Allele frequencies resulting from dosing heterozygous mice at 1.5 mg/kg (301H): p.R83C to p.R83 (correction); p.Y85H bystander mutation; Uncorrected (synonymous) editing (R83C); and Indels ( n = 5). Statistics were performed using a two-tailed unpaired T test. Data are presented as Mean values ± SEM, and individual data points for each animal are displayed. * denotes p < 0.05, ** denotes p value < 0.005.
E. Coli Ftsw Open Reading Frame Encoding The E289g Residue Change, supplied by Twist Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Twist Bioscience dna encoding the twinstrep tag in frame with a snap tag
The 10–12-week-old heterozygous (mR83/huR83C) mice, not fasted, were treated by systemic administration of BEAM-301 and the target site sequence was analyzed one week later via next-generation sequencing (NGS). a Target site sequence for p.R83C to p.R83 correction, the p.R83 synonymous variant and the pathogenic p.Y85H bystander variant. Nucleotides on the complementary strand edited by BEAM-301 are bracketed. b Correlation of dose levels of BEAM-301 to the editing efficiency for the conversion of the p.R83C ( <t>G6PC1</t> - c.247C > T ) variant to wild-type p.R83 ( G6PC1 - c.247 C ) along with the p.Y85H mutation. The n numbers for each dosage of BEAM-301 in mg/kg are listed. c Allele frequencies resulting from dosing heterozygous mice at 1.5 mg/kg (301H): p.R83C to p.R83 (correction); p.Y85H bystander mutation; Uncorrected (synonymous) editing (R83C); and Indels ( n = 5). Statistics were performed using a two-tailed unpaired T test. Data are presented as Mean values ± SEM, and individual data points for each animal are displayed. * denotes p < 0.05, ** denotes p value < 0.005.
Dna Encoding The Twinstrep Tag In Frame With A Snap Tag, supplied by Twist Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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dna encoding the twinstrep tag in frame with a snap tag - by Bioz Stars, 2026-04
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GenScript corporation cdna encoding the open reading frame of human hgsnat
The 10–12-week-old heterozygous (mR83/huR83C) mice, not fasted, were treated by systemic administration of BEAM-301 and the target site sequence was analyzed one week later via next-generation sequencing (NGS). a Target site sequence for p.R83C to p.R83 correction, the p.R83 synonymous variant and the pathogenic p.Y85H bystander variant. Nucleotides on the complementary strand edited by BEAM-301 are bracketed. b Correlation of dose levels of BEAM-301 to the editing efficiency for the conversion of the p.R83C ( <t>G6PC1</t> - c.247C > T ) variant to wild-type p.R83 ( G6PC1 - c.247 C ) along with the p.Y85H mutation. The n numbers for each dosage of BEAM-301 in mg/kg are listed. c Allele frequencies resulting from dosing heterozygous mice at 1.5 mg/kg (301H): p.R83C to p.R83 (correction); p.Y85H bystander mutation; Uncorrected (synonymous) editing (R83C); and Indels ( n = 5). Statistics were performed using a two-tailed unpaired T test. Data are presented as Mean values ± SEM, and individual data points for each animal are displayed. * denotes p < 0.05, ** denotes p value < 0.005.
Cdna Encoding The Open Reading Frame Of Human Hgsnat, supplied by GenScript corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cdna encoding the open reading frame of human hgsnat/product/GenScript corporation
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Cx3cr1-CreERT2 rat creation and characterization overview. ( A ) The Cx3cr1-CreERT2 DNA was injected into Long Evans (LE) rat embryos. ( B ) The double-floxed inverted open reading frame (DIO) was used to produce the DIO-mCherry rat for Cre-dependent expression of the mCherry fluorescent protein in any cells that express Cre. ( C ) The DIO-mCherry rat was crossed with the Cx3cr1-CreERT2 and treated with tamoxifen (TAM) to fluorescently label Cx3cr1 expressing cells such as microglia in the brain. Created in BioRender. Harvey, B. (2025) https://BioRender.com/lf2aj0o .

Journal: Scientific Reports

Article Title: Generation and characterization of a tamoxifen-inducible, Cre driver rat for transgene expression in microglia

doi: 10.1038/s41598-025-31077-z

Figure Lengend Snippet: Cx3cr1-CreERT2 rat creation and characterization overview. ( A ) The Cx3cr1-CreERT2 DNA was injected into Long Evans (LE) rat embryos. ( B ) The double-floxed inverted open reading frame (DIO) was used to produce the DIO-mCherry rat for Cre-dependent expression of the mCherry fluorescent protein in any cells that express Cre. ( C ) The DIO-mCherry rat was crossed with the Cx3cr1-CreERT2 and treated with tamoxifen (TAM) to fluorescently label Cx3cr1 expressing cells such as microglia in the brain. Created in BioRender. Harvey, B. (2025) https://BioRender.com/lf2aj0o .

Article Snippet: The open-reading-frame encoding iCre (based on pBSII-iCre , was amplified by PCR with linkered primers and inserted the BamHI and EcoRI sites of pOTTC293 (Addgene; #60057) using ligation-independent cloning (In-Fusion; Clontech).

Techniques: Injection, Expressing

The 10–12-week-old heterozygous (mR83/huR83C) mice, not fasted, were treated by systemic administration of BEAM-301 and the target site sequence was analyzed one week later via next-generation sequencing (NGS). a Target site sequence for p.R83C to p.R83 correction, the p.R83 synonymous variant and the pathogenic p.Y85H bystander variant. Nucleotides on the complementary strand edited by BEAM-301 are bracketed. b Correlation of dose levels of BEAM-301 to the editing efficiency for the conversion of the p.R83C ( G6PC1 - c.247C > T ) variant to wild-type p.R83 ( G6PC1 - c.247 C ) along with the p.Y85H mutation. The n numbers for each dosage of BEAM-301 in mg/kg are listed. c Allele frequencies resulting from dosing heterozygous mice at 1.5 mg/kg (301H): p.R83C to p.R83 (correction); p.Y85H bystander mutation; Uncorrected (synonymous) editing (R83C); and Indels ( n = 5). Statistics were performed using a two-tailed unpaired T test. Data are presented as Mean values ± SEM, and individual data points for each animal are displayed. * denotes p < 0.05, ** denotes p value < 0.005.

Journal: Nature Communications

Article Title: Base-editing corrects metabolic abnormalities in a humanized mouse model for glycogen storage disease type-Ia

doi: 10.1038/s41467-024-54108-1

Figure Lengend Snippet: The 10–12-week-old heterozygous (mR83/huR83C) mice, not fasted, were treated by systemic administration of BEAM-301 and the target site sequence was analyzed one week later via next-generation sequencing (NGS). a Target site sequence for p.R83C to p.R83 correction, the p.R83 synonymous variant and the pathogenic p.Y85H bystander variant. Nucleotides on the complementary strand edited by BEAM-301 are bracketed. b Correlation of dose levels of BEAM-301 to the editing efficiency for the conversion of the p.R83C ( G6PC1 - c.247C > T ) variant to wild-type p.R83 ( G6PC1 - c.247 C ) along with the p.Y85H mutation. The n numbers for each dosage of BEAM-301 in mg/kg are listed. c Allele frequencies resulting from dosing heterozygous mice at 1.5 mg/kg (301H): p.R83C to p.R83 (correction); p.Y85H bystander mutation; Uncorrected (synonymous) editing (R83C); and Indels ( n = 5). Statistics were performed using a two-tailed unpaired T test. Data are presented as Mean values ± SEM, and individual data points for each animal are displayed. * denotes p < 0.05, ** denotes p value < 0.005.

Article Snippet: A human cDNA encoding the open reading frame for G6PC1 - c.247C > T ( G6PC1 -R83C) were inserted into exon 1 of the mouse G6pc gene at the ATG start codon (Taconic Biosciences) in a way that created a premature STOP codon in the coding sequence of the mouse G6pc exon 1.

Techniques: Sequencing, Next-Generation Sequencing, Variant Assay, Mutagenesis, Two Tailed Test